Title :
The effect of anisotropic permeability on fluid flow and species transport within cortical bone
Author :
Keanini, Russell G.
Author_Institution :
Dept. of Mech. Eng. & Eng. Sci., North Carolina Univ., Charlotte, NC, USA
Abstract :
Investigates the effect of anisotropic permeability on fluid flow and passive non-diffusive species transport in cortical bone. A model is developed which focuses on flow and transport induced by a single blood vessel within a porous anisotropic matrix. Model predictions are found to be qualitatively consistent with experimental observations. More significantly, the model suggests that flow within the cortex can in some instances be determined by local permeability characteristics, independent of the local pressure (stress) gradient. This result challenges the notion that external stress alone determines in-bone flow characteristics
Keywords :
permeability; anisotropic permeability effect; cortical bone; experimental observations; external stress; fluid flow; in-bone flow characteristics; local pressure gradient; model predictions; passive nondiffusive species transport; porous anisotropic matrix; single blood vessel; stress gradient; Anisotropic magnetoresistance; Blood vessels; Bones; Brain modeling; Fluid flow; Irrigation; Mechanical engineering; Permeability; Predictive models; Stress;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.415366
