DocumentCode
2377938
Title
Microfluidic neurotransmiter-based neural interfaces for retinal prosthesis
Author
Iezzi, Raymond ; Finlayson, Paul ; Xu, Yong ; Katragadda, Rakesh
Author_Institution
Mayo Clinic, Rochester, MN, USA
fYear
2009
fDate
3-6 Sept. 2009
Firstpage
4563
Lastpage
4565
Abstract
Natural inter-neuronal communication is mediated primarily via neurotransmitter-gated ion channels. While most of the methods for neural interfacing have been based upon electrical stimulation, neurotransmitter-based approaches for the spatially and temporally controlled delivery of neurotransmitters are relatively new. Methods of neurotransmitter stimulation retinal prosthesis may provide new ways to control neural excitation. Experimental results for retinal ganglion cell stimulation demonstrate the feasibility of a neurotransmitter-based retinal prosthesis.
Keywords
biomembrane transport; eye; microfluidics; neurophysiology; prosthetics; microfluidic neurotransmiter-based neural interfaces; natural interneuronal communication; neural excitation; neural interfacing; neurotransmitter stimulation; neurotransmitter-gated ion channels; retinal ganglion cell stimulation; retinal prosthesis; Animals; Electric Stimulation; Evoked Potentials; Glutamic Acid; Male; Neurotransmitter Agents; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Time Factors;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location
Minneapolis, MN
ISSN
1557-170X
Print_ISBN
978-1-4244-3296-7
Electronic_ISBN
1557-170X
Type
conf
DOI
10.1109/IEMBS.2009.5332694
Filename
5332694
Link To Document