• DocumentCode
    2378321
  • Title

    Cellular Neural Networks, Navier-Stokes equation and microarray image reconstruction

  • Author

    Zineddin, Bachar ; Wang, Zidong ; Liu, Xiaohui

  • Author_Institution
    Dept. of Inf. Syst. & Comput., Brunel Univ., London, UK
  • fYear
    2010
  • fDate
    18-18 Dec. 2010
  • Firstpage
    234
  • Lastpage
    239
  • Abstract
    Despite the latest improvements in the microarray technology, many developments are needed particularly in the image processing stage. Some hardware implementations of microarray image processing have been proposed and proved to be a promising alternative to the currently available software systems. However, the main drawback is the unsuitable addressing of the quantification of the gene spots which depend on many assumptions. It is our aim in this paper to present a new Image Reconstruction algorithm using Cellular Neural Network, which solves the Navier-Stokes equation. This algorithm offers a robust method to estimate the background signal within the gene spot region. Quantitative comparisons are carried out, between our approach and some available methods in terms of objective standpoint. It is shown that the proposed algorithm gives highly accurate and realistic measurements in a fully automated manner, and also, in a remarkably efficient time.
  • Keywords
    Navier-Stokes equations; biological techniques; cellular biophysics; genetics; image reconstruction; lab-on-a-chip; neural nets; DNA microarray; Navier-Stokes equation; cellular neural networks; gene spots; microarray image reconstruction; cDNA microarray reconstruction; cellular neural networks; isotropic diffusion; navier-stokes equation; partial differential equations;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedicine Workshops (BIBMW), 2010 IEEE International Conference on
  • Conference_Location
    Hong, Kong
  • Print_ISBN
    978-1-4244-8303-7
  • Electronic_ISBN
    978-1-4244-8304-4
  • Type

    conf

  • DOI
    10.1109/BIBMW.2010.5703805
  • Filename
    5703805