Title :
Satellite nanoscope and cellular BioASICs for quantitative biomedicine
Author_Institution :
Dept. of Bioeng., Univ. of California, Berkeley, CA, USA
Abstract :
This paper presents satellite nanoscopes and biological application specific integrated circuits (BioASICs). Satellite nanoscope is developed for spectroscopic imaging of living cells, molecular optogenetics (i.e. the remote control of gene regulation and protein expression), and therapeutic applications. Fundamental understanding of living cells via satellite nanoscopes will provide insights of molecular dynamics and signaling pathways in living cells. BioASICs are accomplished to permit precise and repeatable characterizations of cellular activity. These BioASICs are facilitating significant advancements in quantitative cell biology and the foundation for precision biology, cell reprogramming, highspeed biologic microprocessors, drug screening, molecular diagnostics, and personalized medicine.
Keywords :
application specific integrated circuits; biomedical optical imaging; cellular biophysics; molecular electronics; nanobiotechnology; BioASIC; biological application specific integrated circuits; living cells; molecular dynamics; molecular optogenetics; quantitative biomedicine; satellite nanoscope; signaling pathways; spectroscopic imaging; NASBA; Nanoscope; ONCOS; biophotonics; cell culture chip; microfluidics; molecular diagnostics; molecular optogenetics; nanoplasmonics; personalized medicine; quantitative biology; spectroscopic imaging; Animals; Capillary Electrochromatography; Cells; Electronics, Medical; Hela Cells; Humans; Liver, Artificial; Microfluidic Analytical Techniques; Microscopy; Nanotechnology; Rats; Surface Plasmon Resonance; Tissue Array Analysis;
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2009.5332763
