DocumentCode
2380804
Title
Genome-wide DNA methylation analysis in tumor and normal tissues from lung squamous cell carcinoma and serous cystadenocarcinoma
Author
Inaoka, Hidenori ; Noshiro, Makoto ; Fukuoka, Yutaka
Author_Institution
Sch. of Allied Health Sci., Kitasato Univ., Sagamihara, Japan
fYear
2010
fDate
18-18 Dec. 2010
Firstpage
855
Lastpage
856
Abstract
Genome-wide DNA methylation was analysed in tumor and normal tissues. HOXA9, HOXD4, TBX4 were found to be hypermethylated in tumor tissues whereas PAX4 was found to be hypermethylated in normal tissues. HOXD4 and TBX4 are suggested to be potent tumor suppressor genes or tumor suppressor associated genes.
Keywords
DNA; biochemistry; bioinformatics; cancer; cellular biophysics; genetics; genomics; molecular biophysics; tumours; HOXA9; HOXD4; PAX4; TBX4; genome-wide DNA methylation analysis; hypermethylation; lung squamous cell carcinoma; normal tissues; serous cystadenocarcinoma; tumor suppressor associated genes; tumor suppressor genes; DNA methylation; tumor;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedicine Workshops (BIBMW), 2010 IEEE International Conference on
Conference_Location
Hong, Kong
Print_ISBN
978-1-4244-8303-7
Electronic_ISBN
978-1-4244-8304-4
Type
conf
DOI
10.1109/BIBMW.2010.5703943
Filename
5703943
Link To Document