Title :
Functional MRI study of brain function under resting and activated states
Author :
Chen, Wei ; Liu, Xiao ; Zhu, Xiao-Hong ; Zhang, Nanyin
Author_Institution :
Dept. of Radiol., Univ. of Minnesota, Minneapolis, MN, USA
Abstract :
Numerous magnetic resonance imaging (MRI) techniques have been developed with various imaging contrasts, which can be tightly linked to brain functions, electrophysiology and diseases. Recent MRI technology developments have resulted in several important functional MRI (fMRI) methods based on the blood oxygenation level dependent (BOLD) contrast. These fMRI methods have been applied to mapping brain activation in laminar level as well functional connectivity network in a resting brain. We have found a strong correlation between the spontaneous brain activity and BOLD fluctuation indicating a tight neurovascular relation.
Keywords :
bioelectric phenomena; biomedical MRI; blood vessels; brain; diseases; neural nets; neurophysiology; BOLD fluctuation; activated states; blood oxygenation level-dependent contrast; brain activation mapping; brain function; diseases; electrophysiology; functional MRI method; functional connectivity network; laminar level; magnetic resonance imaging techniques; resting states; spontaneous brain activity; tight neurovascular relation; Animals; Brain; Brain Mapping; Cats; Computer Simulation; Diagnostic Imaging; Humans; Magnetic Resonance Imaging; Models, Neurological; Nerve Net; Oxygen; Rats;
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2009.5333175
