Title :
A novel dual mode capacitor biosensor for real-time, label-free DNA detection
Author :
Wang, Y.-B. ; Assefaw-Redda, Y. ; Gabig-Ciminska, M. ; Enfors, S.-O. ; Östling, M. ; Zhang, S.L.
Author_Institution :
KTH, R. Inst. of Technol.
Abstract :
A novel biosensor working in both MOS capacitor and electric double-layer capacitor mode for real-time, label-free DNA detection is presented. The former mode measures density and polarity of charged biomolecules to be monitored, while the latter mode appears to reveal more of surface-molecule interactions and offers high sensitivity and easiness for diagnosis. A combined mode-utilization yields optimal complementary information of significance
Keywords :
DNA; MOS capacitors; biosensors; capacitive sensors; molecular biophysics; MOS capacitor; biomolecules; dual mode capacitor biosensor; electric double-layer capacitor mode; label-free DNA detection; surface-molecule interactions; Biosensors; Capacitive sensors; Channel bank filters; DNA; Electrodes; Gold; MOS capacitors; Molecular biophysics; Monitoring; Probes;
Conference_Titel :
Electron Devices Meeting, 2006. IEDM '06. International
Conference_Location :
San Francisco, CA
Print_ISBN :
1-4244-0438-X
Electronic_ISBN :
1-4244-0439-8
DOI :
10.1109/IEDM.2006.346886
