• DocumentCode
    2397001
  • Title

    Modulation of arousal regulation with central thalamic deep brain stimulation

  • Author

    Shah, Sudhin A. ; Baker, Jonathan L. ; Ryou, Jae-Wook ; Purpura, Keith P. ; Schiff, Nicholas D.

  • Author_Institution
    Physiol., Biophys. & Syst. Biol. Dept., Weill Cornell Grad. Sch. of Biomed. Sci., New York, NY, USA
  • fYear
    2009
  • fDate
    3-6 Sept. 2009
  • Firstpage
    3314
  • Lastpage
    3317
  • Abstract
    To investigate the effects of central thalamic deep brain stimulation (CT/DBS) on behavior and frontal cortical function, we conducted experiments in an awake, behaving macaque monkey performing tasks that required sustained attention and working memory. Results of this preliminary study revealed that CT/DBS can lead to an improvement, a decrement, a mixed or have no effect on behavior.
  • Keywords
    bioelectric potentials; brain; medical signal processing; neurophysiology; patient treatment; arousal regulation modulation; central thalamic deep brain stimulation; sustained attention; working memory; Adult; Animals; Arousal; Attention; Behavior; Behavior, Animal; Brain; Deep Brain Stimulation; Electrophysiology; Humans; Macaca; Male; Memory, Short-Term; Neural Pathways; Neurons;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
  • Conference_Location
    Minneapolis, MN
  • ISSN
    1557-170X
  • Print_ISBN
    978-1-4244-3296-7
  • Electronic_ISBN
    1557-170X
  • Type

    conf

  • DOI
    10.1109/IEMBS.2009.5333751
  • Filename
    5333751