Title :
Numerical models of laser fusion of intestinal tissues
Author_Institution :
Electr. & Comput. Eng., Univ. of Texas at Austin, Austin, TX, USA
Abstract :
Numerical models of continuous wave Tm:YAG thermal fusion in rat intestinal tissues were compared to experiment. Optical and thermal FDM models that included tissue damage based on Arrhenius kinetics were used to predict birefringence loss in collagen as the standard of comparison. The models also predicted collagen shrinkage, jellification and water loss. The inclusion of variable optical and thermal properties is essential to achieve favorable agreement between predicted and measured damage boundaries.
Keywords :
biological tissues; biomolecular effects of radiation; biothermics; birefringence; laser applications in medicine; proteins; surgery; Arrhenius kinetics; birefringence loss; collagen; collagen shrinkage; intestinal tissues; jellification; laser fusion; optical FDM model; thermal FDM model; thermal fusion; thermal properties; tissue damage; water loss; Algorithms; Animals; Collagen; Hot Temperature; Hyperthermia, Induced; Intestines; Kinetics; Lasers; Models, Theoretical; Normal Distribution; Rats; Reproducibility of Results; Temperature; Time Factors;
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2009.5333797
