Numerical models of laser fusion of intestinal tissues

Author

Pearce, John A.

Author_Institution

Electr. & Comput. Eng., Univ. of Texas at Austin, Austin, TX, USA

fYear

2009

fDate

3-6 Sept. 2009

Firstpage

4303

Lastpage

4306

Abstract

Numerical models of continuous wave Tm:YAG thermal fusion in rat intestinal tissues were compared to experiment. Optical and thermal FDM models that included tissue damage based on Arrhenius kinetics were used to predict birefringence loss in collagen as the standard of comparison. The models also predicted collagen shrinkage, jellification and water loss. The inclusion of variable optical and thermal properties is essential to achieve favorable agreement between predicted and measured damage boundaries.

Keywords

biological tissues; biomolecular effects of radiation; biothermics; birefringence; laser applications in medicine; proteins; surgery; Arrhenius kinetics; birefringence loss; collagen; collagen shrinkage; intestinal tissues; jellification; laser fusion; optical FDM model; thermal FDM model; thermal fusion; thermal properties; tissue damage; water loss; Algorithms; Animals; Collagen; Hot Temperature; Hyperthermia, Induced; Intestines; Kinetics; Lasers; Models, Theoretical; Normal Distribution; Rats; Reproducibility of Results; Temperature; Time Factors;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE

Conference_Location

Minneapolis, MN

ISSN

1557-170X

Print_ISBN

978-1-4244-3296-7

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2009.5333797

Filename

5333797