DocumentCode
2398301
Title
Validation of human skin models in the MHz region
Author
Huclova, Sonja ; Fröhlich, Jürg ; Falco, Lisa ; Dewarrat, François ; Talary, Mark S. ; Vahldieck, Rüdiger
Author_Institution
Lab. for Electromagn. Fields & Microwave Electron., ETH Zurich, Zurich, Switzerland
fYear
2009
fDate
3-6 Sept. 2009
Firstpage
4461
Lastpage
4464
Abstract
The human skin consists of several layers with distinct dielectric properties. Resolving the impact of changes in dielectric parameters of skin layers and predicting them allows for non-invasive sensing in medical diagnosis. So far no complete skin and underlying tissue model is available for this purpose in the MHz range. Focusing on this dispersion-dominated frequency region multilayer skin models are investigated: First, containing homogeneous non-dispersive sublayers and second, with sublayers obtained from a three-phase Maxwell-Garnett mixture of shelled cell-like ellipsoids. Both models are numerically simulated using the Finite Element Method, a fringing field sensor on the top of the multilayer system serving as a probe. Furthermore, measurements with the sensor probing skin in vivo are performed. In order to validate the models the uppermost skin layer, the stratum corneum was i) included and ii) removed in models and measurements. It is found that only the Maxwell-Garnett mixture model can qualitatively reproduce the measured dispersion which still occurs without the stratum corneum and consequently, structural features of tissue have to be part of the model.
Keywords
biomedical imaging; dielectric properties; finite element analysis; multilayers; skin; Maxwell-Garnett mixture model; dielectric properties; dispersion-dominated frequency region; finite element method; fringing field sensor; homogeneous nondispersive sublayers; human skin models; medical diagnosis; multilayer skin model; shelled cell-like ellipsoids; stratum corneum; three-phase Maxwell-Garnett mixture; Computer Simulation; Electric Conductivity; Epidermis; Finite Element Analysis; Humans; Models, Biological; Reproducibility of Results; Skin Physiological Phenomena; Subcutaneous Fat;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location
Minneapolis, MN
ISSN
1557-170X
Print_ISBN
978-1-4244-3296-7
Electronic_ISBN
1557-170X
Type
conf
DOI
10.1109/IEMBS.2009.5333820
Filename
5333820
Link To Document