• DocumentCode
    2398301
  • Title

    Validation of human skin models in the MHz region

  • Author

    Huclova, Sonja ; Fröhlich, Jürg ; Falco, Lisa ; Dewarrat, François ; Talary, Mark S. ; Vahldieck, Rüdiger

  • Author_Institution
    Lab. for Electromagn. Fields & Microwave Electron., ETH Zurich, Zurich, Switzerland
  • fYear
    2009
  • fDate
    3-6 Sept. 2009
  • Firstpage
    4461
  • Lastpage
    4464
  • Abstract
    The human skin consists of several layers with distinct dielectric properties. Resolving the impact of changes in dielectric parameters of skin layers and predicting them allows for non-invasive sensing in medical diagnosis. So far no complete skin and underlying tissue model is available for this purpose in the MHz range. Focusing on this dispersion-dominated frequency region multilayer skin models are investigated: First, containing homogeneous non-dispersive sublayers and second, with sublayers obtained from a three-phase Maxwell-Garnett mixture of shelled cell-like ellipsoids. Both models are numerically simulated using the Finite Element Method, a fringing field sensor on the top of the multilayer system serving as a probe. Furthermore, measurements with the sensor probing skin in vivo are performed. In order to validate the models the uppermost skin layer, the stratum corneum was i) included and ii) removed in models and measurements. It is found that only the Maxwell-Garnett mixture model can qualitatively reproduce the measured dispersion which still occurs without the stratum corneum and consequently, structural features of tissue have to be part of the model.
  • Keywords
    biomedical imaging; dielectric properties; finite element analysis; multilayers; skin; Maxwell-Garnett mixture model; dielectric properties; dispersion-dominated frequency region; finite element method; fringing field sensor; homogeneous nondispersive sublayers; human skin models; medical diagnosis; multilayer skin model; shelled cell-like ellipsoids; stratum corneum; three-phase Maxwell-Garnett mixture; Computer Simulation; Electric Conductivity; Epidermis; Finite Element Analysis; Humans; Models, Biological; Reproducibility of Results; Skin Physiological Phenomena; Subcutaneous Fat;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
  • Conference_Location
    Minneapolis, MN
  • ISSN
    1557-170X
  • Print_ISBN
    978-1-4244-3296-7
  • Electronic_ISBN
    1557-170X
  • Type

    conf

  • DOI
    10.1109/IEMBS.2009.5333820
  • Filename
    5333820