DocumentCode :
2399304
Title :
Identification of markers of cardiovascular disease in women and the reconstruction of its corresponding protein interaction network
Author :
Camargo, A. ; Kim, J.T.
Author_Institution :
Sch. of Comput., Univ. of East Anglia, Norwich, UK
fYear :
2009
fDate :
3-6 Sept. 2009
Firstpage :
6963
Lastpage :
6968
Abstract :
Cardiovascular disease is the second most prevalent cause of morbidity and mortality in women of developed countries. Although it is well established that gender is a risk factor for cardiovascular disease, most gene expression analysis studies favour the identification of disease bio-markers and potential drug targets over combined populations. This study integrates genomic and systems approaches to identify a female-related set of genes that intervene in signal and metabolic pathways leading to cardiovascular disease.
Keywords :
cardiovascular system; diseases; drugs; genetics; genomics; molecular biophysics; proteins; cardiovascular disease marker identification; drug targets; gene expression analysis; genomic approach; metabolic pathways; protein interaction network; risk factor; Biological Markers; Biomedical Engineering; Cardiovascular Diseases; Female; Gene Expression Profiling; Genetic Markers; Humans; Metabolic Networks and Pathways; Protein Interaction Mapping; Systems Biology;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
ISSN :
1557-170X
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
Type :
conf
DOI :
10.1109/IEMBS.2009.5333879
Filename :
5333879
Link To Document :
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