DocumentCode :
2400755
Title :
Correlation between visual stimulus eccentricity and multiscale neuronal activity in the lateral geniculate nucleus
Author :
Farkas, Ágnes ; Tsarouchas, Nikolaos ; Gombkötö, Péter ; Nagy, Attila ; Benedek, György ; Bezerianos, Anastasios ; Berényi, Antal
Author_Institution :
Dept. of Physiol., Univ. of Szeged, Szeged, Hungary
fYear :
2009
fDate :
3-6 Sept. 2009
Firstpage :
6810
Lastpage :
6813
Abstract :
Single unit activity (SUA) was extensively studied in the lateral geniculate nucleus (LGN) but less attention was paid to the analysis of the local field potentials (LFP). In the present study, we investigate how and to what extent LFP and SUA correlate with visual stimulus eccentricity. SUAs and LFPs recorded extracellularly from 52 electrode positions were analyzed. Both LFP and SUA recordings contained well defined time-segments, which correlated with stimulus eccentricity. The spectral analysis of the LFPs indicated that in addition to the phasic, short latency activity of the 20 Hz frequency band, a tonic, 2-10 Hz, elongated component was also present. The time-domain analysis of the phasic and tonic LFP segments revealed a non-linear decrease of the mean LFP amplitude. The frequency-domain investigation made it obvious that the low and high frequency components exhibit a spatially localized increase of the response, in contrast to the time-domain curve. Our results confirm that the local field potentials as a measure of the mesoscopic level neuronal activity provide additional information concerning the activity of neuronal populations, thus enhancing our present knowledge about the functional circuitry as the foundation of various neuronal processes.
Keywords :
brain; cellular biophysics; frequency-domain analysis; neurophysiology; time-domain analysis; visual evoked potentials; bandwidth 20 Hz; extracellular recording; frequency 2 Hz to 10 Hz; frequency-domain analysis; functional circuitry; lateral geniculate nucleus; local field potential; mesoscopic level neuronal activity; multiscale neuronal activity; neuronal population activity; short latency activity; single unit activity; spectral analysis; time-domain analysis; visual stimulus eccentricity; Animals; Cats; Geniculate Bodies; Neurons; Photic Stimulation; Time Factors; Visual Fields;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
ISSN :
1557-170X
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
Type :
conf
DOI :
10.1109/IEMBS.2009.5333974
Filename :
5333974
Link To Document :
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