Title : 
Design of a low-voltage instrumentation amplifier for enzyme-extended-gate field effect transistor based urea sensor application
         
        
            Author : 
Chung, Wen-Yaw ; Yeh, Mao-Hsiang ; Chen, Jia-Chyi ; Shen-Kan Hsiung ; Pijanowska, D.G. ; Torbicz, Wladyslaw ; Chou, Jung-Chuan ; Sun, Tai-Ping
         
        
            Author_Institution : 
Inst. of Electron. Eng., Chung Yuan Christian Univ., Chung-li, Taiwan
         
        
        
        
        
        
            Abstract : 
This paper presents a low-voltage operated instrumentation amplifier design for enzyme-extended-gate field-effect transistor (EEGFET) biosensor signal readout applications. The instrumentation amplifier built by three bulk-driven amplifiers fabricated in a 0.5 μm double-poly double-metal CMOS technology and other off-chip resistors has been proved to have a potential application in urea sensor signal sensing. Key parameters of the bulk-driven amplifier and the instrumentation amplifier have been verified for the low-voltage signal readout consideration. The system for urea monitoring has been performed with 1.5 V power supply. Experiment results show that the developed instrumentation amplifier has an acceptable sensing response of various urea concentrations in the range of 0.3125 to 240mg/dl
         
        
            Keywords : 
biosensors; chemical sensors; instrumentation amplifiers; ion sensitive field effect transistors; 0.5 micron; 1.5 V; biosensor signal readout; bulk-driven amplifiers; double-poly double-metal CMOS technology; enzyme-extended-gate field effect transistor; low-voltage instrumentation amplifier; off-chip resistors; sensing response; urea sensor; Conferences; Electronic equipment testing; FETs; Instruments;
         
        
        
        
            Conference_Titel : 
Electronic Design, Test and Applications, 2002. Proceedings. The First IEEE International Workshop on
         
        
            Conference_Location : 
Christchurch
         
        
            Print_ISBN : 
0-7695-1453-7
         
        
        
            DOI : 
10.1109/DELTA.2002.994610