Title :
Stretchable bioelectrodes
Author_Institution :
Sch. of Electr. & Comput. Eng., Purdue Univ., West Lafayette, IN, USA
Abstract :
In this paper, we present a stretchable electrode array for studying cell behavior subjected to mechanical strain. The electrode array consists of four gold nail-head pins (250 mum tip diameter and 1.75 mm spacing) inserted into a polydimethylsiloxane (PDMS) platform (25.4 times 25.4 mm2). Fusible indium alloy (liquid at room temperature) filled microchannels are used to connect the electrodes to the outside, thus providing the required stretchability. The electrode platform is biocompatible and can withstand strains of up to 40%. We tested these electrodes by repeatedly (100 times) subjecting them to 35% strain and did not notice any failure. We also successfully cultured mice cardiomyocytes onto the platform and performed electrical pacing.
Keywords :
bioMEMS; biomechanics; biomedical electrodes; cardiology; cellular biophysics; gold; indium alloys; microelectrodes; microfabrication; Au; InJkJk; cell behavior; cultured mice cardiomyocytes; electrical pacing; fusible indium alloy filled microchannels; gold nail-head pins; mechanical strain; polydimethylsiloxane platform; size 1.75 mm; size 250 mum; stretchable bioelectrode electrode; temperature 293 K to 298 K; Elastic Modulus; Electric Impedance; Electrodes; Epoxy Compounds; Equipment Design; Equipment Failure Analysis; Polymers; Reproducibility of Results; Sensitivity and Specificity;
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2009.5334302
