μ-cell fatigue test

Author

Fukui, Wataru ; Kaneko, Makoto ; Sakuma, Shinya ; Kawahara, Tomohiro ; Arai, Fumihito

Author_Institution

Dept. of Mech. Eng., Osaka Univ., Suita, Japan

fYear

2012

fDate

14-18 May 2012

Firstpage

4600

Lastpage

4605

Abstract

A new concept of μ-cell fatigue test is proposed. By reciprocating a cell across the throat of a micro channel repeatedly, the dynamic deformation behavior of the cell is measured. We define a new index of fatigue characteristics of cells as the number of reciprocatory motion leading to a prescribed recovery ratio. The test system is composed of a piezoelectric (PZT) actuator, a high speed vision sensor and a micro channel with a throat. Preliminary experiments were conducted by using Red Blood Cells (RBCs). The result suggested that the activation level of a cell can be evaluated based on its fatigue characteristics.

Keywords

bioMEMS; biomechanics; blood; cellular biophysics; deformation; fatigue; fatigue testing; image sensors; microchannel flow; piezoelectric actuators; recovery; μ-cell fatigue test; dynamic deformation; high speed vision sensor; microchannel; piezoelectric actuator; reciprocatory motion; recovery ratio; red blood cells; Actuators; Cameras; Diseases; Fatigue; Indexes; Microchannel; Sensors;

fLanguage

English

Publisher

ieee

Conference_Titel

Robotics and Automation (ICRA), 2012 IEEE International Conference on

Conference_Location

Saint Paul, MN

ISSN

1050-4729

Print_ISBN

978-1-4673-1403-9

Electronic_ISBN

1050-4729

Type

conf

DOI

10.1109/ICRA.2012.6224856

Filename

6224856