DocumentCode
2413417
Title
Sparse nonnegative matrix factorization with the elastic net
Author
Liu, Weixiang ; Zheng, Songfeng ; Jia, Sen ; Shen, Linlin ; Fu, Xianghua
Author_Institution
Dept. of Biomed. Eng., Shenzhen Univ., Shenzhen, China
fYear
2010
fDate
18-21 Dec. 2010
Firstpage
265
Lastpage
268
Abstract
Nonnegative matrix factorization is used extensively for feature extraction and clustering analysis. Recently many sparsity/sparseness constraints, such as L1 penalty, are introduced for sparse nonnegative matrix factorization. Inspired by sparsity measures from linear regression model, this paper proposes to integrate nonnegative matrix factorization with another sparsity constraint, the elastic net. The experimental results of clustering analysis on three gene expression datasets demonstrate the effectiveness of the proposed method.
Keywords
bioinformatics; feature extraction; genetics; pattern clustering; regression analysis; sparse matrices; clustering analysis; elastic net; feature extraction; gene expression; linear regression model; sparse nonnegative matrix factorization; Accuracy; Bioinformatics; Cancer; Data analysis; Encoding; Gene expression; Sparse matrices; Nonnegative matrix factorization; clustering analysis; gene expression data; sparsity penalty;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedicine (BIBM), 2010 IEEE International Conference on
Conference_Location
Hong Kong
Print_ISBN
978-1-4244-8306-8
Electronic_ISBN
978-1-4244-8307-5
Type
conf
DOI
10.1109/BIBM.2010.5706574
Filename
5706574
Link To Document