• DocumentCode
    2414755
  • Title

    Ranking SVM for multiple kernels output combination in protein-protein interaction extraction from biomedical literature

  • Author

    Yang, Zhihao ; Lin, Yuan ; Wu, Jiajin ; Tang, Nan ; Lin, Hongfei ; Li, Yanpeng

  • Author_Institution
    Dept. of Comput. Sci. & Eng., Dalian Univ. of Technol., Dalian, China
  • fYear
    2010
  • fDate
    18-21 Dec. 2010
  • Firstpage
    595
  • Lastpage
    598
  • Abstract
    Knowledge about protein-protein interactions unveils the molecular mechanisms of biological processes. This paper presents a multiple kernels learning-based approach to automatically extracting protein-protein interactions from biomedical literature. Experimental evaluations show that our approach can achieve state-of-the-art performance with respect to comparable evaluations, with 64.88% F-score and 88.02% area under the receiver operating characteristics curve (AUC) on the AImed corpus.
  • Keywords
    biology computing; learning (artificial intelligence); proteins; sensitivity analysis; support vector machines; AImed corpus; F-score; biomedical literature; learning; molecular mechanisms; multiple kernels output combination; protein-protein interaction extraction; ranking SVM; receiver operating characteristics curve; Data mining; Feature extraction; Kernel; Protein engineering; Proteins; Support vector machines; Training; Multiple kernels learning; Protein-protein interaction; Support Vector Machines;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedicine (BIBM), 2010 IEEE International Conference on
  • Conference_Location
    Hong Kong
  • Print_ISBN
    978-1-4244-8306-8
  • Electronic_ISBN
    978-1-4244-8307-5
  • Type

    conf

  • DOI
    10.1109/BIBM.2010.5706635
  • Filename
    5706635