Title :
Active CMOS Array for Electrochemical Sensing of Biomolecules
Author :
Levine, Peter M. ; Gong, Ping ; Shepard, Kenneth L. ; Levicky, Rastislav
Author_Institution :
Columbia Univ., New York
Abstract :
We describe the design of a 4times4 active sensor array for multiplexed electrochemical biomolecular detection in a 0.25-mum-CMOS process. Integrated potentiostats sense the current flowing through the on-chip Au electrodes that result from reactions occurring at the chip surface. Preliminary experimental results include cyclic voltammetry of several redox species and application to DNA probe coverage characterization.
Keywords :
CMOS integrated circuits; DNA; electrochemical electrodes; electrochemical sensors; gold; molecular biophysics; sensor arrays; Au; DNA probe; active CMOS array; active sensor array; biomolecular detection; biomolecules; cyclic voltammetry; electrochemical sensing; gold electrodes; integrated potentiostats; multiplexed electrochemical detection; size 0.25 mum; Biomedical measurements; CMOS process; Circuits; Current measurement; DNA; Electrodes; Molecular biophysics; Probes; Sensor arrays; Sensor phenomena and characterization;
Conference_Titel :
Custom Integrated Circuits Conference, 2007. CICC '07. IEEE
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-4244-1623-3
Electronic_ISBN :
978-1-4244-1623-3
DOI :
10.1109/CICC.2007.4405855
