DocumentCode
2416604
Title
A CMOS Array Sensor for Sub-800-ps Time-Resolved Fluorescence Detection
Author
Huang, T. ; Sorgenfrei, S. ; Shepard, K.L. ; Gong, P. ; Levicky, R.
Author_Institution
Columbia Univ., New York
fYear
2007
fDate
16-19 Sept. 2007
Firstpage
829
Lastpage
832
Abstract
This paper describes the design of an active CMOS sensor array for fluorescence applications which enables time-gated, time-resolved fluorescence spectroscopy. The 64 times 64 array is sensitive to photon densities as low as 8 times 106 photons/cm with 64-point averaging and, through a differential pixel design, has a measured impulse response of better than 800 ps. Applications include both active microarrays and high-frame-rate imagers for fluorescence lifetime imaging microscopy.
Keywords
CMOS image sensors; fluorescence spectroscopy; sensor arrays; CMOS array sensor; active CMOS sensor array; differential pixel design; fluorescence applications; fluorescence detection; fluorescence lifetime imaging microscopy; fluorescence spectroscopy; high-frame-rate imagers; impulse response; photon density; Biosensors; Chemical and biological sensors; Chemical engineering; Decoding; Detectors; Fluorescence; Microscopy; Optical filters; Optoelectronic and photonic sensors; Sensor arrays;
fLanguage
English
Publisher
ieee
Conference_Titel
Custom Integrated Circuits Conference, 2007. CICC '07. IEEE
Conference_Location
San Jose, CA
Print_ISBN
978-1-4244-1623-3
Electronic_ISBN
978-1-4244-1623-3
Type
conf
DOI
10.1109/CICC.2007.4405856
Filename
4405856
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