• DocumentCode
    2416604
  • Title

    A CMOS Array Sensor for Sub-800-ps Time-Resolved Fluorescence Detection

  • Author

    Huang, T. ; Sorgenfrei, S. ; Shepard, K.L. ; Gong, P. ; Levicky, R.

  • Author_Institution
    Columbia Univ., New York
  • fYear
    2007
  • fDate
    16-19 Sept. 2007
  • Firstpage
    829
  • Lastpage
    832
  • Abstract
    This paper describes the design of an active CMOS sensor array for fluorescence applications which enables time-gated, time-resolved fluorescence spectroscopy. The 64 times 64 array is sensitive to photon densities as low as 8 times 106 photons/cm with 64-point averaging and, through a differential pixel design, has a measured impulse response of better than 800 ps. Applications include both active microarrays and high-frame-rate imagers for fluorescence lifetime imaging microscopy.
  • Keywords
    CMOS image sensors; fluorescence spectroscopy; sensor arrays; CMOS array sensor; active CMOS sensor array; differential pixel design; fluorescence applications; fluorescence detection; fluorescence lifetime imaging microscopy; fluorescence spectroscopy; high-frame-rate imagers; impulse response; photon density; Biosensors; Chemical and biological sensors; Chemical engineering; Decoding; Detectors; Fluorescence; Microscopy; Optical filters; Optoelectronic and photonic sensors; Sensor arrays;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Custom Integrated Circuits Conference, 2007. CICC '07. IEEE
  • Conference_Location
    San Jose, CA
  • Print_ISBN
    978-1-4244-1623-3
  • Electronic_ISBN
    978-1-4244-1623-3
  • Type

    conf

  • DOI
    10.1109/CICC.2007.4405856
  • Filename
    4405856