Title :
Influences of bilateral ischemic stroke on the cortical synchronization
Author :
Wu, Wenqing ; Jin, Zheng ; Qiu, Yihong ; Zhu, Yisheng ; Li, Yingjie ; Tong, Shanbao
Author_Institution :
Dept. of Biomed. Eng., Shanghai Jiao Tong Univ., Shanghai, China
Abstract :
Stroke has been one of the leading causes of mortality and long-term morbidity around the world. Describing the cortical synchrony has been useful in understanding of central nervous system disorders after brain injury. In this paper, we investigated the large scale cortical phase synchronization derived from multichannel electroencephalogram (EEG) recordings of bilateral ischemic stroke patients(n = 9). Compared with the results from the age- and gender-matched control subjects (n = 8), stroke patients showed 1) there were not significant changes of the intra-hemispheric synchronization after the bilateral stroke; and however, 2) both global and inter-hemispheric synchronization are vulnerable to the ischemic injury. Our preliminary results indicated that synchrony analysis of the spontaneous scalp EEG during at resting state provided new insight into cortical functional disorder following stroke.
Keywords :
electroencephalography; neurophysiology; age-matched control subject; bilateral ischemic stroke patients; cortical functional disorder; cortical synchronization; gender-matched control subject; inter-hemispheric synchronization; intra-hemispheric synchronization; large scale cortical phase synchronization; multichannel electroencephalogram recordings; Aged; Aged, 80 and over; Biomedical Engineering; Brain Ischemia; Brain Mapping; Cerebral Cortex; Cortical Synchronization; Electroencephalography; Female; Humans; Male; Middle Aged; Models, Neurological; Models, Statistical; Signal Processing, Computer-Assisted; Stroke;
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2009.5334870