DocumentCode :
2423243
Title :
Functional MRI at 1.5T
Author :
Singh, M. ; Kim, H. ; Kim, T. ; Khosia, D.
Author_Institution :
Dept. of Radiol. & Biomed. Eng., Southern California Edison Co., Los Angeles, CA, USA
fYear :
1993
fDate :
31 Oct-6 Nov 1993
Firstpage :
1475
Abstract :
Human studies were conducted to determine the feasibility of functional MRI during auditory stimulation using conventional hardware (i.e., without echo-planar imaging) in a Philips 1.5T Gyroscan system. A gradient-echo pulse sequence was optimized to minimize the effect of gradient sound. Simple tonal stimulation and linguistic stimuli designed to activate regions responsible for comprehension were investigated. Also, functional images in response to visual and somatosensory stimulation were generated, albeit with a different gradient-echo sequence to optimize contrast and temporal resolution. A registration technique was developed to reduce head motion artifacts. Cerebrospinal fluid pulsation artifacts however, were not removable even with flow compensating gradient pulses. The resulting functional images indicate a 3-9% increase in signal intensity, localized to the corresponding auditory, visual or somatosensory brain regions during stimulation
Keywords :
biomedical NMR; brain; hearing; 1.5 T; Philips 1.5 T Gyroscan system; auditory stimulation; brain regions activation; cerebrospinal fluid pulsation artifacts; comprehension; contrast optimization; flow compensating gradient pulses; functional MRI; gradient sound effect minimization; head motion artifacts reduction; linguistic stimuli; optimized gradient-echo pulse sequence; registration technique; signal intensity; simple tonal stimulation; somatosensory stimulation; temporal resolution; visual stimulation; Acoustic noise; Blood flow; Coils; Ear; Head; Image resolution; Magnetic resonance imaging; Natural languages; Positron emission tomography; Signal resolution;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Nuclear Science Symposium and Medical Imaging Conference, 1993., 1993 IEEE Conference Record.
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-1487-5
Type :
conf
DOI :
10.1109/NSSMIC.1993.373532
Filename :
373532
Link To Document :
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