DocumentCode :
2427025
Title :
Optimum control mode analysis and numerical backtracking of microfluidic cell-secreted analyte detection
Author :
Wang, Shiying ; Wang, Wei
Author_Institution :
Sch. of Phys., Peking Univ., Beijing, China
fYear :
2010
fDate :
20-23 Jan. 2010
Firstpage :
272
Lastpage :
275
Abstract :
Presently, due to the important applications in various clinical diagnoses and drug analyses, cell-secreted analyte detection, especially based on a microfluidic operation principle, has attracted tremendous interests. In this work, optimum control mode for this microfluidics biosensing process is identified based on a numerically obtained phase chart. Normally there are four control modes, namely flow control mode, surface reaction control mode, diffusion control mode along the flowing direction and diffusion control mode vertically to the flowing direction. The diffusion control mode along the flowing direction, with a slower diffusion process along the flowing direction, is the optimal detection scheme, where cell-secreted analyte production in source can be successfully backtracked from signals obtained in detection regions.
Keywords :
bioMEMS; biological techniques; biomedical measurement; cellular biophysics; flow control; microfluidics; diffusion control mode; flow control mode; flowing direction control mode; microfluidic biosensing process; microfluidic cell secreted analyte detection; numerical backtracking; optimum control mode analysis; phase chart; surface reaction control mode; Control mode Cell-secreted analyte detection Microfluidic Numerical backtracking;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Nano/Micro Engineered and Molecular Systems (NEMS), 2010 5th IEEE International Conference on
Conference_Location :
Xiamen
Print_ISBN :
978-1-4244-6543-9
Type :
conf
DOI :
10.1109/NEMS.2010.5592207
Filename :
5592207
Link To Document :
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