Design and analysis of SOI based biosensor with integrated optic readout

Author

Malathi, Sathish ; Rani, K.R. ; Srinivas, T.

Author_Institution

Dept. of Electr. & Commun. Eng., Indian Inst. of Sci., Bangalore, India

fYear

2010

fDate

29-31 July 2010

Firstpage

1

Lastpage

3

Abstract

In this paper we have proposed and analyzed a novel integrated optic racetrack resonator based biosensor. The device is capable of distinguishing compressive and tensile stresses on a cantilever due to conformational changes of protein. We have considered Bovine Serum Albumin (BSA) and Immunoglobulin G (IgG). The change of surface stress upon adsorption of IgG is compressive and of BSA is tensile. When the biomolecules adhere to the device surface, due to photo elastic effect the effective refractive index and length of racetrack resonator change. Our simulation results show that the resonant wavelength shifts by 0.3196 × 10^-3 nm/ με which is a measure of surface stress.

Keywords

bioMEMS; biological techniques; cantilevers; integrated optics; micro-optomechanical devices; microsensors; molecular biophysics; molecular configurations; optical resonators; optical sensors; proteins; refractive index; silicon-on-insulator; BSA; IgG; Si-Jk; adsorption; biomolecules; biosensor; bovine serum albumin; cantilever; compressive stress; conformation; immunoglobulin; integrated optic racetrack resonator; integrated optic readout; photoelastic effect; protein; refractive index; surface stress; tensile stress; Biomedical optical imaging; Optical ring resonators; Optical sensors; Optical variables control; Optical waveguides;

fLanguage

English

Publisher

ieee

Conference_Titel

Computing Communication and Networking Technologies (ICCCNT), 2010 International Conference on

Conference_Location

Karur

Print_ISBN

978-1-4244-6591-0

Type

conf

DOI

10.1109/ICCCNT.2010.5592574

Filename

5592574