Title :
Accuracy of differential expression detection with compressed microarray images
Author :
Xu, Qian ; Jianping Hua ; Xiong, Zixiang ; Bittner, Michael L. ; Dougherty, Edward R.
Author_Institution :
Dept of Electr. & Comput. Eng., Texas A & M Univ., College Station, TX
Abstract :
Current gene-expression microarrays carry an enormous amount of information. This paper examines lossy SPIHT and JPEG 2000 compression of oligo microarray images and addresses the accuracy of differential expression detection with compressed images. Experiments show that the identification disagreement rate for all genes monotonically increases with the compression ratio, but is still under 1.5% at 20:1 compression with both SPIHT and JPEG 2000.
Keywords :
data compression; image coding; JPEG 2000 compression; SPIHT; compressed microarray images; differential expression detection; gene-expression microarrays; oligo microarray images; Arithmetic; Bioinformatics; Genomics; Humans; ISO; Image coding; Image storage; Transform coding; Wavelet coefficients; Wavelet domain;
Conference_Titel :
Genomic Signal Processing and Statistics, 2006. GENSIPS '06. IEEE International Workshop on
Conference_Location :
College Station, TX
Print_ISBN :
1-4244-0384-7
Electronic_ISBN :
1-4244-0385-5
DOI :
10.1109/GENSIPS.2006.353147
