• DocumentCode
    2442597
  • Title

    Homomorphisms of probabilistic gene regulatory networks

  • Author

    Avinó, María Alicia

  • Author_Institution
    Dept. of Mathematic-Phys., Univ. of Puerto Rico, Cayey
  • fYear
    2006
  • fDate
    28-30 May 2006
  • Firstpage
    85
  • Lastpage
    86
  • Abstract
    In this paper we study finite dynamical systems with n functions acting on the same set X, and probabilities assigned to these functions, that it is called probabilistic regulatory gene networks (PRN) in [3]. This concept is the same or a natural generalization of the concept probabilistic Boolean networks (PBN), introduced by I. Shmulevich, E. Dougherty, and W. Zhang in [5], Particularly the model PBN has been using to describe genetic networks and has therapeutic applications, see [6]. In PRN the most important question is to describe the steady states of the systems, so in this paper we pay attention to the idea of transforming a network to another without lost all the properties, in particular the probability distribution. Following this objective we develop the concepts of homomorphism and e-homomorphism of probabilistic regulatory networks, since these concepts bring the properties from one networks to another. Projections are special homomorphisms, and they always induce invariant subnetworks that contain cycles and steady states.
  • Keywords
    Boolean functions; biology computing; genetics; probability; set theory; e-homomorphism; finite dynamical system; finite set; probabilistic Boolean network; probabilistic gene regulatory network; probability distribution; Genetics; Probability distribution; State-space methods; Steady-state;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Genomic Signal Processing and Statistics, 2006. GENSIPS '06. IEEE International Workshop on
  • Conference_Location
    College Station, TX
  • Print_ISBN
    1-4244-0384-7
  • Electronic_ISBN
    1-4244-0385-5
  • Type

    conf

  • DOI
    10.1109/GENSIPS.2006.353168
  • Filename
    4161789