Optimizing Sequence of Enhanced External Counter-Pulsation during AEI-CPR Based on Genetic Algorithm

Enhanced External Counter-Pulsation (EECP) was lower limbs-compression equipment for cardiopulmonary resuscitation (CPR) that enhanced blood regurgitation during recoil phase of chest compression. This paper describes optimizing sequence of the EECP for a CPR technique - Active Compression-Decompression CPR with EECP and Inspiratory Impedance Threshold Valve (AEI-CPR). A mathematical model of human circulatory system used to research AEI-CPR has been established. And then the hemodynamic effects of AEI-CPR to the blood circulatory system model were performed on the model. To improve the aortic pressure and myocardial perfusion pressure during cardiac arrest, an optimization algorithm, based on genetic algorithm, were used to find optimum sequence of the EECP when other parameters of external force for AEI-CPR were definite. Applying the optimization algorithm on the mathematical model, the optimum sequence of the EECP had been found. And the experiment results indicated that obvious hemodynamic effects were attained when the EECP began compression at the end of chest compression.