Analysis of order preserving genes biclusters

In this paper, we describe an approach for finding all order preserving genes biclusters from a set of DNA microarray experimental data that combines the algorithm that finds biclusters with constant values on columns developed in one of our previous study with an adaptive gene expression level quantization procedure. All the biclusters discovered with the proposed methodology have no imperfections and, the complexity of the algorithm is shown to be lower than that of previous approaches. Application of the method to ovarian cancer data seems to reveal significant local pattern.