Title :
3D Ultrasound System for Analysis of Carotid Plaque Progression and Regression
Author :
Fenster, A. ; Chiu, B. ; Landry, A. ; Spence, J.D. ; Parraga, G.E.
Author_Institution :
Imaging Res. Labs., Robarts Res. Inst., London, ON
fDate :
Oct. 29 2006-Nov. 1 2006
Abstract :
Morphological characterization of carotid plaques has been used for risk stratification and evaluation of response to therapy, evaluation of new risk factors, genetic research, and for quantifying effects of new anti-atherosclerotic therapies. We developed a 3D US system that allows detailed studies of carotid plaques in 3D. Our software includes 3D reconstruction, viewing, and manual and semi-automated segmentation of carotid plaques. We evaluated our plaque quantification software by examining plaque volume measurement accuracy, variability, and plaque surface morphology. Our results indicate that our approach is sensitive tool and can be used in studies of atherosclerotic plaque progression and regression.
Keywords :
biomedical measurement; biomedical ultrasonics; cardiology; genetics; image reconstruction; image segmentation; medical image processing; regression analysis; 3D reconstruction; 3D ultrasound system; anti-atherosclerotic therapy; carotid plaque progression analysis; genetic research; image segmentation; morphological characterization; plaque quantification software; plaque volume measurement accuracy; regression analysis; risk factor evaluation; Area measurement; Carotid arteries; Genetics; Medical treatment; Monitoring; Neck; Surface morphology; Thickness measurement; Transducers; Ultrasonic imaging;
Conference_Titel :
Signals, Systems and Computers, 2006. ACSSC '06. Fortieth Asilomar Conference on
Conference_Location :
Pacific Grove, CA
Print_ISBN :
1-4244-0784-2
Electronic_ISBN :
1058-6393
DOI :
10.1109/ACSSC.2006.355108
