Representation of myocardium depolarization by simple models

Simulated myocardium activation and body surface potentials were used to study the abilities of multipolar (MP), multidipolar (MD) and uniform double layer (UDL) models to represent the depolarization dynamics. Body surface potentials computed from the estimated model solutions were in good agreement with the original simulated potentials. In all models the correlation was above 0.94 and rms error was less than 12%. Epicardial activation sequence was estimated directly in the UDL model and indirectly (using the minimal derivation criterion on pericardial potential tracings) in the MP and MD models. Unsatisfactory results were obtained for most unregularized solutions and not very good results for MP and MD models. Best performing was the regularized UDL model solution (correlation 0.915, rms error 4.2%). Despite important simplifications in the experiment the authors believe that some solutions for UDL and MD models could be used to recognize different activation patterns