DocumentCode
2465903
Title
"Metabolic Control Analysis" from a Control Theoretic Perspective
Author
Ingalls, Brian P.
Author_Institution
Dept. of Appl. Math., Waterloo Univ., Ont.
fYear
2006
fDate
13-15 Dec. 2006
Firstpage
2116
Lastpage
2121
Abstract
A theory of control of biochemical systems developed by the theoretical biology community is interpreted from a control-theoretic point of view. This theory, known as metabolic control analysis (MCA), is based on an extension of parametric sensitivity analysis to stoichiometric systems. The main results of MCA are shown to correspond to particular solutions of an appropriately stated tracking problem. This presentation leads to some natural generalizations of existing results
Keywords
biochemistry; biocontrol; sensitivity analysis; stoichiometry; biochemical system control theory; metabolic control analysis; parametric sensitivity analysis; stoichiometric system; theoretical biology community; tracking problem; Biochemical analysis; Biochemistry; Biological control systems; Control system analysis; Control systems; Feedback control; Mathematics; Sensitivity analysis; Steady-state; USA Councils;
fLanguage
English
Publisher
ieee
Conference_Titel
Decision and Control, 2006 45th IEEE Conference on
Conference_Location
San Diego, CA
Print_ISBN
1-4244-0171-2
Type
conf
DOI
10.1109/CDC.2006.377367
Filename
4177139
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