Title :
Computer aided measurement of local myocardial perfusion in MRI
Author :
Yang, Xin ; Taeymans, Yves ; Carlier, Pierre ; Verstraeten, Koen ; Brunfaut, Marnic ; Cornelis, Jan
Author_Institution :
IRIS/ETRO, Vrije Univ., Brussels, Belgium
Abstract :
Gadolinium-DTPA has been proved to be a safe and adequate contrast agent for MRI studies of ischemic heart disease. An important problem arising in quantitative image sequence analysis is the heart movement, mainly due to respiration. An X window based interactive software package allows one to align the images, to calculate regional perfusion-time curves and parametric images showing the maximal perfusion speed. A typical analysis procedure starts with the computer assisted detection of the outer contours of the heart. Based on the calculation of the centre of gravity of the heart region, alignment is carried out. Several regions of interest can now be selected in order to measure the regional perfusion characteristics. The parametric image, showing the maximal perfusion speed, appears to be particularly useful for delineating regions of reduced perfusion
Keywords :
biomedical NMR; biomedical measurement; cardiology; haemorheology; medical image processing; muscle; Gd; MRI; X window based interactive software package; computer aided measurement; gadolinium-DTPA; heart movement; heart outer contours; images alignment; local myocardial perfusion; magnetic resonance imaging; maximal perfusion speed; medical diagnostic imaging; parametric images; quantitative image sequence analysis; reduced perfusion regions delineation; regional perfusion characteristics; regional perfusion-time curves; Cardiology; Gravity; Heart; Image segmentation; Image sequence analysis; Image sequences; Magnetic resonance imaging; Myocardium; Pixel; Visualization;
Conference_Titel :
Computers in Cardiology 1993, Proceedings.
Conference_Location :
London
Print_ISBN :
0-8186-5470-8
DOI :
10.1109/CIC.1993.378428
