Control aspects of left ventricular wall thickness in pressure overload left ventricular hypertrophy

Author

Feng, Minjie ; Drzewiecki, Gary M. ; Li, John K-J.

Author_Institution

Dept. of Biomed. Eng., Rutgers Univ., Piscataway, NJ, USA

fYear

2002

fDate

2002

Firstpage

37

Lastpage

38

Abstract

A negative feedback control model was developed to predict left ventricular (LV) wall thickness growth over a long time period following the elevation of peak systolic pressure to prescribed values. Time series plots, phase plots and delay maps were obtained for both wall thickness growth with and without delay. LV wall thickness steady-state values were found to change proportionally to the peak systolic pressure

Keywords

biocontrol; cardiology; haemodynamics; physiological models; time series; Laplace law; adaptive process; canine heart; delay concept; delay maps; increased hemodynamic loading; left ventricular wall thickness; long time period; mathematical model; myocardial fiber level; negative feedback control model; peak systolic pressure elevation; phase plots; pressure overload left ventricular hypertrophy; steady-state values; time series plots; Delay effects; Hemodynamics; Hypertension; Myocardium; Negative feedback; Negative feedback loops; Pressure control; Steady-state; Stress; Thickness control;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 2002. Proceedings of the IEEE 28th Annual Northeast

Conference_Location

Philadelphia, PA

Print_ISBN

0-7803-7419-3

Type

conf

DOI

10.1109/NEBC.2002.999453

Filename

999453