Normal aging and brain functional connectivity of primary motor cortex: a functional MRI (fMRI) study

Author

Niazy, Rami K. ; Qiu, Maolin ; Deng, Zhensheng ; Enderle, John ; Lai, Song

Author_Institution

Biomed. Eng. Dept., Connecticut Univ., Storrs, CT, USA

fYear

2002

fDate

2002

Firstpage

153

Lastpage

154

Abstract

Functional magnetic resonance imaging (fMRI) techniques and image processing tools have been applied to investigate the effects of normal aging on brain functional connectivity of primary motor cortex. Task activation and resting state fMRI time series images of healthy young and elderly subjects were collected, and then activation and connectivity maps were constructed for the two age groups. Preliminary results tend to suggest that primary motor cortex functional connectivity is not altered by normal aging. Work is in progress to refine image post-processing algorithms and to study more subjects

Keywords

biomedical MRI; brain; geriatrics; haemodynamics; medical image processing; time series; BOLD signals; activation maps; brain functional connectivity; connectivity maps; elderly subjects; functional MRI; hemodynamic fluctuations; image post-processing algorithms; normal aging effects; primary motor cortex; resting state; task activation; temporal correlation; time series images; young subjects; Aging; Biomedical imaging; Blood flow; Brain; Computed tomography; Fluctuations; Frequency; Hemodynamics; Image processing; Magnetic resonance imaging;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 2002. Proceedings of the IEEE 28th Annual Northeast

Conference_Location

Philadelphia, PA

Print_ISBN

0-7803-7419-3

Type

conf

DOI

10.1109/NEBC.2002.999511

Filename

999511