The effect of pump rate and filling on hemolysis in a pulsatile left ventricular assist device (LVAD)

Author

Lukic, Branka ; Weiss, William

Author_Institution

Dept. of Bioeng., Pennsylvania State Univ., Hershey, PA, USA

fYear

2002

fDate

2002

Firstpage

181

Lastpage

182

Abstract

An in-vitro hemolysis study has been conducted in order to determine the effects of pump rate and pump filling in the Penn State-Arrow left ventricular assist device. The nominal pump rates observed were 120 or 70 beats per minute, and the nominal pump filling was maintained in either the normal range (97%) or the abnormal range (84%). A new small volume mock circulatory loop has been designed and assembled which closely mimics clinical operating conditions. This study showed that incomplete filling is more hemolytic than increased pump rate in the case of these nominal parameters

Keywords

biocontrol; cardiology; flow control; haemodynamics; prosthetics; pulsatile flow; pumps; valves; LionHeart system; clinical operating conditions; hemodynamic properties; implantable system; in-vitro hemolysis; incomplete filling; monostrut valves; pulsatile left ventricular assist device; pump filling effect; pump rate effect; small volume mock circulatory loop; unidirectional flow; Batteries; Biomedical engineering; Blood; Brushless DC motors; Clamps; Filling; Pumps; Stress; Surgery; Valves;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 2002. Proceedings of the IEEE 28th Annual Northeast

Conference_Location

Philadelphia, PA

Print_ISBN

0-7803-7419-3

Type

conf

DOI

10.1109/NEBC.2002.999525

Filename

999525