Expression for the intracellular potential in a cell monolayer due to exposure to an extremely low frequency electromagnetic field

Author

Sreedharan, V. ; Zhang, D.

Author_Institution

Dept. of Mech. & Aerosp. Eng., Rutgers Univ., Piscataway, NJ, USA

fYear

2002

fDate

2002

Firstpage

201

Lastpage

202

Abstract

We have utilized the method of Fromter to model the intracellular potential distribution in an osteoblast monolayer. This model treats the monolayer as a transmission line in the form of a thin, circular membranelike sheet, i.e., Heaviside´s Bessel Cable. Furthermore, the influence of gap-junctional coupling on the potential distribution has been accounted for to a certain extent in this model

Keywords

bioelectric potentials; biological effects of fields; biomagnetism; biomembrane transport; bone; boundary-value problems; finite difference methods; physiological models; ELF electromagnetic field exposure; Heaviside´s Bessel cable; boundary conditions; boundary value problem; circular membrane-like sheet; closely packed membrane protein assemblies; coupling length; cytoplasm resistivity; finite difference schemes; gap-junctional coupling; induced transmembrane potential; intracellular potential distribution; membrane capacitance; osteoblast cell monolayer; time membrane constant; transmission line model; Biomechanics; Biomembranes; Bones; Electromagnetic fields; Frequency; Immune system; In vitro; Laboratories; Power cables; Transmission lines;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 2002. Proceedings of the IEEE 28th Annual Northeast

Conference_Location

Philadelphia, PA

Print_ISBN

0-7803-7419-3

Type

conf

DOI

10.1109/NEBC.2002.999535

Filename

999535