Title :
Expression for the intracellular potential in a cell monolayer due to exposure to an extremely low frequency electromagnetic field
Author :
Sreedharan, V. ; Zhang, D.
Author_Institution :
Dept. of Mech. & Aerosp. Eng., Rutgers Univ., Piscataway, NJ, USA
Abstract :
We have utilized the method of Fromter to model the intracellular potential distribution in an osteoblast monolayer. This model treats the monolayer as a transmission line in the form of a thin, circular membranelike sheet, i.e., Heaviside´s Bessel Cable. Furthermore, the influence of gap-junctional coupling on the potential distribution has been accounted for to a certain extent in this model
Keywords :
bioelectric potentials; biological effects of fields; biomagnetism; biomembrane transport; bone; boundary-value problems; finite difference methods; physiological models; ELF electromagnetic field exposure; Heaviside´s Bessel cable; boundary conditions; boundary value problem; circular membrane-like sheet; closely packed membrane protein assemblies; coupling length; cytoplasm resistivity; finite difference schemes; gap-junctional coupling; induced transmembrane potential; intracellular potential distribution; membrane capacitance; osteoblast cell monolayer; time membrane constant; transmission line model; Biomechanics; Biomembranes; Bones; Electromagnetic fields; Frequency; Immune system; In vitro; Laboratories; Power cables; Transmission lines;
Conference_Titel :
Bioengineering Conference, 2002. Proceedings of the IEEE 28th Annual Northeast
Conference_Location :
Philadelphia, PA
Print_ISBN :
0-7803-7419-3
DOI :
10.1109/NEBC.2002.999535
