DocumentCode :
2472249
Title :
Feedback Control of an LVAD Supporting a Failing Cardiovascular System Regulated by the Baroreflex
Author :
Chen, Shaohui ; Ferreira, Antonio ; Simaan, Marwan A. ; Boston, J. Robert ; Antaki, James F.
Author_Institution :
Dept. of Electr. Eng., Pittsburgh Univ., PA
fYear :
2006
fDate :
13-15 Dec. 2006
Firstpage :
655
Lastpage :
660
Abstract :
The baroreflex is an internal feedback mechanism that stabilizes the blood pressure in the circulatory system. Its function in patients with congestive heart failure is preserved fairly well. When these patients are implanted with a left ventricular assist device (LVAD), the baroreflex plays an important role in interacting with the controller that regulates the pump speed. In this paper, we consider a combined model of the cardiovascular system, the baroreflex mechanism, and an LVAD. We present results that will describe the interaction mechanisms between these three subsystems. We then propose a feedback controller for the LVAD which automatically adjust its speed based on the systemic vascular resistance (SVR) and heart rate (HR) under varying patient conditions. Simulation results show that the combined model is capable of reproducing human responses to exercise and the proposed controller is able to respond to change in physiological state of patients with heart failure
Keywords :
cardiology; feedback; medical control systems; prosthetics; LVAD; baroreflex; blood pressure; circulatory system; congestive heart failure; failing cardiovascular system; feedback control; heart rate; internal feedback mechanism; left ventricular assist device; systemic vascular resistance; Adaptive control; Automatic control; Baroreflex; Blood pressure; Cardiovascular system; Circulatory system; Feedback control; Heart rate; Humans; Immune system;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Decision and Control, 2006 45th IEEE Conference on
Conference_Location :
San Diego, CA
Print_ISBN :
1-4244-0171-2
Type :
conf
DOI :
10.1109/CDC.2006.377383
Filename :
4177454
Link To Document :
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