Title :
Functional analysis of histone deacetylase RPD3/HDA1 family in Physcomitrella patens by bioinformatics
Author :
Fu, Wenqun ; Chen, Zhengbin ; Lin, Ying ; Wang, Yuling ; Li, Li ; Teng, Xiaoling ; Fu, Jinmei ; Li, Xiaoqing
Author_Institution :
Dept. of Biol. & Biotechnol., Zhangzhou Normal Coll., Zhangzhou, China
Abstract :
The biological function of RPD3/HDA1 HDACs family from Physcomitrella patens was investigated by using bioinformatics. The results showed that the members of RPD3/HDA1 HDACs family were localized in different subcellular localization of P. patens, and their encoding proteins all have four sites, such as the protein kinase C phosphorylation site, the Casein kinase II phosphorylation site, the N-glycosylation site, and the N-myristoylation site. The RPD3/HDA1 HDACs members all have no transmembrane regions and they are hydrophilic proteins without signal peptide. The RPD3/HDA1 HDACs members from P. patens were aligned by ClustalW2 and their HDACs domains are highly conserved. These RPD3/HDA1 HDACs seemed to be involved in processes, such as transcription regulation, energy metabolism and chromatin silencing in P. patens.
Keywords :
biochemistry; bioinformatics; biomembranes; cellular biophysics; enzymes; hydrophilicity; molecular biophysics; Casein kinase II phosphorylation site; N-glycosylation site; N-myristoylation site; Physcomitrella patens; bioinformatics; biological function; chromatin silencing; energy metabolism; functional analysis; histone deacetylase RPD3/HDA1 family; hydrophilic proteins; phosphorylation site; physcomitrella patens; protein kinase C; signal peptide; subcellular localization; transcription regulation; transmembrane regions; Bioinformatics; Biological information theory; DNA; Humans; Presence network agents; Proteins; Bioinformatics; Physcomitrella patens; RPD3/HDA1 HDACs; histone deacetylase;
Conference_Titel :
Remote Sensing, Environment and Transportation Engineering (RSETE), 2011 International Conference on
Conference_Location :
Nanjing
Print_ISBN :
978-1-4244-9172-8
DOI :
10.1109/RSETE.2011.5965941
