Chronic stimulation of the semicircular canals using a multichannel vestibular prosthesis: Effects on locomotion and angular vestibulo-ocular reflex in chinchillas

Author

Sun, Daniel Q. ; Rahman, Mehdi A. ; Fridman, Gene ; Dai, Chenkai ; Chiang, Bryce ; Della Santina, Charles C.

Author_Institution

Sch. of Med., Dept. of Otolaryngology-Head & Neck Surg., Johns Hopkins Univ., Baltimore, MD, USA

fYear

2011

fDate

Aug. 30 2011-Sept. 3 2011

Firstpage

3519

Lastpage

3523

Abstract

Bilateral loss of vestibular sensation causes difficulty maintaining stable vision, posture and gait. An implantable prosthesis that partly restores vestibular sensation could significantly improve quality of life for individuals disabled by this disorder. We have developed a head-mounted multichannel vestibular prosthesis (MVP) that restores sufficient semicircular canal function to recreate a 3D angular vestibulo-ocular reflex (aVOR). In this study, we evaluated effects of chronic MVP stimulation on locomotion in chinchillas. Two of three animals examined exhibited significant improvements in both locomotion and aVOR.

Keywords

prosthetics; 3D angular vestibulo-ocular reflex; bilateral loss; chinchillas; chronic MVP stimulation; chronic stimulation; head-mounted multichannel vestibular prosthesis; implantable prosthesis; locomotion; semicircular canal function; vestibular sensation; Animals; Frequency modulation; Head; Irrigation; Prosthetics; Three dimensional displays; Animals; Chinchilla; Electrodes; Locomotion; Reflex, Vestibulo-Ocular; Semicircular Canals;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE

Conference_Location

Boston, MA

ISSN

1557-170X

Print_ISBN

978-1-4244-4121-1

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2011.6090584

Filename

6090584