Title : 
On automated assessment of Levodopa-induced dyskinesia in Parkinson´s disease
         
        
            Author : 
Tsipouras, Markos G. ; Tzallas, Alexandros T. ; Fotiadis, Dimitrios I. ; Konitsiotis, Spyridon
         
        
            Author_Institution : 
Dept. of Mater. Sci. & Eng., Univ. of Ioannina, Ioannina, Greece
         
        
        
            fDate : 
Aug. 30 2011-Sept. 3 2011
         
        
        
        
            Abstract : 
A method for the analysis of accelerometer and gyroscope signals in order to automatically assess the Levodopa-induced dyskinesia (LID) in patients with Parkinson´s disease is presented in this paper. Several accelerometers and gyroscopes are placed on certain positions on the subject´s body and the obtained signals are analyzed in order to extract several features that depict the energy distribution over the frequency spectrum and the non-linear properties of the signal. These features are fed into an artificial neural network which is used for LID detection and severity classification. The method has been evaluated using a group of 29 subjects. Results are presented related to the body locations that the accelerometers and the gyroscopes are placed. The obtained results indicate high classification ability (84.3% average classification accuracy).
         
        
            Keywords : 
accelerometers; biomedical measurement; diseases; gyroscopes; neural nets; LID detection; Levodopa induced dyskinesia; Parkinson´s disease; accelerometer; artificial neural network; energy distribution spectrum; gyroscope signals; severity classification; Accelerometers; Accuracy; Feature extraction; Gyroscopes; Legged locomotion; Parkinson´s disease; Wrist; Antiparkinson Agents; Automation; Dyskinesias; Humans; Levodopa; Parkinson Disease;
         
        
        
        
            Conference_Titel : 
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
         
        
            Conference_Location : 
Boston, MA
         
        
        
            Print_ISBN : 
978-1-4244-4121-1
         
        
            Electronic_ISBN : 
1557-170X
         
        
        
            DOI : 
10.1109/IEMBS.2011.6090736