DocumentCode
2481304
Title
Synthesis of novel antofine and Cryptopleurine analogues
Author
Song, Yanling ; Meng, Yanqiu
Author_Institution
Dept. of Pharm. Eng., Shenyang Univ. of Chem. Technol., Shenyang, China
fYear
2011
fDate
24-26 June 2011
Firstpage
7928
Lastpage
7931
Abstract
Antofine and Cryptopleurine, natural products belong to the phenanthroindolizidine and phenanthroquinolizidine group of alkaloids, have attracted much attention because of their extremely potent inhibition of cancer cell growth. In this paper, seven analogues with different substituents on phenanthrene ring were designed and synthesized, the chemical structures of these derivatives were characterized by MS and 1H-NMR.
Keywords
biological NMR; cancer; mass spectra; molecular biophysics; molecular configurations; organic compounds; 1H-NMR technique; Antofine analogues; Cryptopleurine analogues; MS technique; alkaloids; cancer cell growth; chemical structure; phenanthrene ring; phenanthroindolizidine group; phenanthroquinolizidine group; Cryptography; Heating; Nitrogen; Silicon compounds; Solvents; Suspensions; Antofine; Cryptopleurine; analogues; design; synthesis;
fLanguage
English
Publisher
ieee
Conference_Titel
Remote Sensing, Environment and Transportation Engineering (RSETE), 2011 International Conference on
Conference_Location
Nanjing
Print_ISBN
978-1-4244-9172-8
Type
conf
DOI
10.1109/RSETE.2011.5966287
Filename
5966287
Link To Document