Title :
Toxicity of cobalt Oxide Nanoparticles
Author :
Rebello, Valeta ; Shaikh, Shamshad ; Desai, P.V.
Author_Institution :
Dept. of Zoology, Goa Univ., Taleigao Plateau, India
Abstract :
The cytotoxicity of CoO nanoparticles on two micro algae (Navicula sp. and Chetoceros sp.) and Bivalve Gill cells was investigated. Cytotoxicity was determined by cellular morphological changes and LDH (Lactose Dehydrogenase), AP (Acid phosphatase) assays. It is observed that CoO nanoparticles have a detrimental effect on microalgae, promoting shrinkage and cell death. There was a significant increase in percentage of cell death when microalgae were exposed to different concentrations of CoO Nanoparticles. Increase in cell death was accompanied by elevation in LDH and acid phosphatase release indicating cell necrosis/cell injuries. Cell Necrosis was observed when Bivalve gill cells were exposed to different concentrations of CoO Nanoparticles.
Keywords :
biomedical materials; cellular biophysics; cobalt compounds; microorganisms; nanobiotechnology; nanoparticles; CoO; acid phosphatase assay; acid phosphatase release; bivalve gill cells; cell death; cell injuries; cell necrosis; cellular morphological changes; cobalt oxide nanoparticles; cytotoxicity; detrimental effect; lactose dehydrogenase assay; microalgae; shrinkage; Biological system modeling; Chemical elements; Nanoparticles; Bivalve; Cobalt Oxide; Microalgae; Toxicity;
Conference_Titel :
Environmental Engineering and Applications (ICEEA), 2010 International Conference on
Conference_Location :
Singapore
Print_ISBN :
978-1-4244-8619-9
Electronic_ISBN :
978-1-4244-8621-2
DOI :
10.1109/ICEEA.2010.5596127
