Title : 
Feasibility investigation of exposed-core fiber for methadone sensing in biological fluids
         
        
            Author : 
Palmisano, T. ; Prudenzano, F. ; De Sario, M. ; Mescia, L. ; Warren-Smith, S.C. ; Monro, T.M.
         
        
            Author_Institution : 
Dipt. di Ing. dell´´Ambiente e per lo Sviluppo Sostenibile, Politec. di Bari, Bari, Italy
         
        
        
        
        
        
            Abstract : 
In this paper, we explore numerically the feasibility of a methadone sensor based on novel exposed-core optical fiber coated with a sensitive polymeric layer. The sensor characteristics have been simulated using the Finite Element Method (FEM). In particular, we have shown that the sensor performance can be enhanced, more specifically the minimum detectable concentration of methadone can be reduced, via a suitable choice of the fiber cross section.
         
        
            Keywords : 
biosensors; drugs; fibre optic sensors; finite element analysis; polymer films; biological fluids; exposed-core optical fiber; fiber cross section; finite element method; methadone sensor; sensitive polymeric layer coating; Absorption; Optical fiber polarization; Optical fiber sensors; Polymers; Propagation losses; Solids; evanescent waves; exposed-core; methadone; optical biosensor;
         
        
        
        
            Conference_Titel : 
Medical Measurements and Applications Proceedings (MeMeA), 2011 IEEE International Workshop on
         
        
            Conference_Location : 
Bari
         
        
            Print_ISBN : 
978-1-4244-9336-4
         
        
        
            DOI : 
10.1109/MeMeA.2011.5966774