Title :
A hydrogel actuated microdispensing device
Author :
Eddington, D.T. ; Beebe, D.J.
Author_Institution :
Dept. of Biomed. Eng., Wisconsin Univ., Madison, WI, USA
Abstract :
In this paper, fabrication of a microdispensing device is demonstrated using stacked micromolding methods and liquid phase photopolymerization. By coupling a volume change of a pH responsive acrylic-acid hydroxymethacrylate (AA-HEMA) copolymer, pressure is generated to effectively empty a reservoir. The device reliably generated a pressure of 3500 N/m2 with a stroke volume of 32.7 μL.
Keywords :
biomedical materials; drug delivery systems; pH; polymer gels; PDMS membrane; dispensing functionality; effective reservoir emptying; liquid phase photopolymerization; micro total analysis; pH responsive acrylic-acid hydroxymethacrylate copolymer; precise fluid dispensing; stacked micromolding; stroke volume; volume change; Biomedical engineering; Biomembranes; Drug delivery; Fabrication; Microfluidics; Pressure measurement; Reservoirs; Soft lithography; Transducers; Volume measurement;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1053045
