Title :
Nanoparticle-assisted DNA nanosensor
Author :
Li, Xin ; Qian, Jun ; Chen, Lili ; Zhu, Ying ; Fang, Qun ; He, S.
Abstract :
We report a sensitive nanosensor based on a micro-fluidic chip and nanoparticles to detect low concentrations of DNA. The emission of CdSe/ZnS-QDs linked with single strand DNAs was quenched by gold nanoparticles linked with the complementary sequences after hybridization. Sensitively detected signal of DNA was obtained from a 100 mum capillary.
Keywords :
DNA; II-VI semiconductors; bioMEMS; biosensors; cadmium compounds; gold; microsensors; nanoparticles; semiconductor heterojunctions; semiconductor quantum dots; wide band gap semiconductors; zinc compounds; Au; CdSe-ZnS; DNA nanosensor; gold nanoparticles; microfluidic chip; quantum dots; Biomedical optical imaging; Biosensors; Biotechnology; DNA; Gold; Nanoparticles; Optical sensors; Probes; Sequences; Zinc compounds;
Conference_Titel :
Optical Fiber Communication and Optoelectronics Conference, 2007 Asia
Conference_Location :
Shanghai
Print_ISBN :
978-0-9789217-2-9
Electronic_ISBN :
978-0-9789217-2-9
DOI :
10.1109/AOE.2007.4410711
