Modulation of peripheral nerve excitability by high frequency ultrasound

Author

Phillips, W.B. ; Martineau, R.L. ; Sweeney, J.D. ; Towe, B.C.

Author_Institution

Dept. of Bioeng., Arizona State Univ., Tempe, AZ, USA

Volume

3

fYear

2002

fDate

23-26 Oct. 2002

Firstpage

2103

Abstract

High frequency tone bursts of ultrasound are capable of suppressing and enhancing peripheral nerve action potential events. An in vitro frog sciatic nerve preparation was used as a biological model. The peak intensity of the sound delivered to the nerve was 150-200 W/cm². Tone bursts consisted of 0.5 to 75 ms pulses delivered at a rate of 1-10 Hz and had center frequencies between 17 and 20 MHz.

Keywords

bioelectric potentials; biological effects of acoustic radiation; biomedical ultrasonics; neurophysiology; ultrasonic effects; 0.5 to 75 ms; 17 to 20 MHz; biological model; electrical stimulation; high frequency tone bursts; high frequency ultrasound; in vitro frog sciatic nerve preparation; peripheral nerve action potential events; peripheral nerve excitability modulation; Acoustic transducers; Data acquisition; Electrical stimulation; Electrodes; Frequency; Pulse amplifiers; Space vector pulse width modulation; Switches; Ultrasonic imaging; Ultrasonic transducers;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint

ISSN

1094-687X

Print_ISBN

0-7803-7612-9

Type

conf

DOI

10.1109/IEMBS.2002.1053189

Filename

1053189