Aqueous humor and iris mechanics in synechial closure in primary angle-closure glaucoma

Author

Huang, E.C. ; Heys, J.J. ; Barocas, V.H.

Author_Institution

Dept. of Chem. Eng. & Material Sci., Minnesota Univ., Minneapolis, MN, USA

Volume

3

fYear

2002

fDate

23-26 Oct. 2002

Firstpage

2147

Abstract

Primary angle-closure glaucoma features a narrow anterior chamber angle in which the anteriorly positioned iris blocks aqueous humor outflow through the trabecular meshwork, subsequently increasing the intraocular pressure. A mathematical model is used to investigate the aqueous humor-iris interaction in synechial angle closure. The model predicted increased intraocular pressure as the anterior chamber angle decreased and a plateau iris configuration in synechial angle closure - consistent with clinical observations.

Keywords

biomechanics; diseases; eye; physiological models; anterior chamber angle; aqueous humor-iris interaction; clinical observations; eye angle-closure; intraocular pressure; iris mechanics; mathematical model; primary angle-closure glaucoma; synechial closure; Adhesives; Biomedical engineering; Chemical engineering; Cornea; Iris; Lenses; Materials science and technology; Mathematical model; Mathematics; Predictive models;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint

ISSN

1094-687X

Print_ISBN

0-7803-7612-9

Type

conf

DOI

10.1109/IEMBS.2002.1053211

Filename

1053211