DocumentCode
2493342
Title
Modeling biochemical networks and excitation-contraction coupling
Author
Saucerman, J.J. ; Michailova, A.P. ; McCulloch, D.
Author_Institution
Dept. of Bioeng., Univ. of California, San Diego, CA, USA
Volume
3
fYear
2002
fDate
23-26 Oct. 2002
Firstpage
2235
Abstract
Integrative computational models are being developed to couple biochemical networks with the physiological functions that they regulate. Models of interacting cell sub-systems including signal transduction, electrophysiology and metabolism are presented. These models allow us to explore hypotheses regarding physiological and pathophysiological function in the cardiac myocyte.
Keywords
biochemistry; bioelectric phenomena; calcium; cardiology; muscle; physiological models; Ca; biochemical networks modeling; cardiac myocyte; electrophysiology; excitation-contraction coupling; heart muscle cells; interacting cell sub-systems models; metabolism; pathophysiological function; physiological functions regulation; Biochemical analysis; Biochemistry; Biomedical computing; Biomedical engineering; Biophysics; Calcium; Computer networks; Kinetic theory; Proteins; Regulators;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
ISSN
1094-687X
Print_ISBN
0-7803-7612-9
Type
conf
DOI
10.1109/IEMBS.2002.1053258
Filename
1053258
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