Title :
Surface plasmonic microscopy for live cell membrane imaging
Author :
He, Ruei-Yu ; Su, Yuan-Deng ; Chiu, Kuo-Chih ; Wu, Hua-Lin ; Lin, Chi-Hung ; Chang, Guan-Liang ; Chen, Shean-Jen
Author_Institution :
Nat. Cheng Kung Univ., Tainan
Abstract :
This study presents a surface plasmon-enhanced total internal reflection fluorescence microscopy (TIRFM) and a surface plasmon polariton (SPP) phase microscopy techniques to image live cell membranes. In the surface plasmon-enhanced TIRFM, the developed microscopy technique is successfully applied to the real-time observation of the thrombomodulin proteins of live cell membranes.
Keywords :
biomedical optical imaging; biomembranes; cellular biophysics; fluorescence spectroscopy; fluorescent lamps; molecular biophysics; optical microscopy; proteins; surface plasmons; cell membrane imaging; surface plasmon polariton phase microscopy; surface plasmon-enhanced total internal reflection fluorescence microscopy; thrombomodulin proteins; Biomembranes; Cells (biology); Fluorescence; Laser beams; Microscopy; Optical films; Optical imaging; Optical interferometry; Plasmons; Proteins;
Conference_Titel :
Optical Fiber Communication and Optoelectronics Conference, 2007 Asia
Conference_Location :
Shanghai
Print_ISBN :
978-0-9789217-2-9
Electronic_ISBN :
978-0-9789217-2-9
DOI :
10.1109/AOE.2007.4410899
