• DocumentCode
    2495098
  • Title

    Real-time Detection of Protein Interactions Using Pyrolyzed Carbon

  • Author

    Lee, Jung A ; Lee, Seung S. ; Lee, Kwang-Cheol ; Park, Se II

  • Author_Institution
    Korea Adv. Inst. of Sci. & Technol., Daejeon
  • fYear
    2006
  • fDate
    22-25 Oct. 2006
  • Firstpage
    628
  • Lastpage
    630
  • Abstract
    We present label-free, real-time detection of streptavidin binding using the pyrolyzed carbon with a p-type conduction behavior in aqueous solution, which is functionalized with amine-conjugated biotin. Pyrolyzed carbon derived from AZ 5214E are fabricated by photolithography and photoresist thermal decomposition in a N2 atmosphere. The streptavidin-biotin interactions on the pyrolyzed carbon are detected successfully by current change after streptavidin binding.
  • Keywords
    photolithography; pyrolysis; amine-conjugated biotin; aqueous solution; p-type conduction behavior; photolithography; photoresist thermal decomposition; protein interactions; pyrolyzed carbon; real-time detection; streptavidin binding; streptavidin-biotin interactions; Atmosphere; Conductivity; Electrical resistance measurement; Electrodes; Fabrication; Gold; Lithography; Proteins; Resists; Temperature;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Sensors, 2006. 5th IEEE Conference on
  • Conference_Location
    Daegu
  • ISSN
    1930-0395
  • Print_ISBN
    1-4244-0375-8
  • Electronic_ISBN
    1930-0395
  • Type

    conf

  • DOI
    10.1109/ICSENS.2007.355546
  • Filename
    4178698
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=2495098