Predicting phosphene elicitation in patients with retinal implants: A mathematical study

Author

Savage, Craig O. ; Grayden, David B. ; Meffin, Hamish ; Burkitt, Anthony N.

Author_Institution

Dept. of Electr. & Electron. Eng., Univ. of Melbourne, Melbourne, VIC, Australia

fYear

2011

fDate

Aug. 30 2011-Sept. 3 2011

Firstpage

6246

Lastpage

6249

Abstract

Single pulse waveforms were considered in a recent model for phosphene elicitation in patients with a retinal prosthesis. Waveforms are constrained to charge-balanced stimuli consisting of a single cathodic and anodic pulse pair. Mathematical models of such stimuli have been constructed and presented based upon patient testimonials. In this work, we derive analytic expressions that may be employed to determine equibrightness levels for different waveforms. We provide an example calculation to show quantitative improvements in stimulation efficiency that are consistent with qualitative findings on waveform effects.

Keywords

artificial organs; eye; physiological models; charge-balanced stimuli; equibrightness levels; phosphene elicitation; retinal prosthesis; single pulse waveforms; Brightness; Delay; Electrical stimulation; Numerical models; Predictive models; Retina; Visualization; Algorithms; Electric Stimulation; Electrodes; Electrophysiology; Humans; Light; Models, Statistical; Models, Theoretical; Nonlinear Dynamics; Phosphenes; Prostheses and Implants; Retina; Retinal Degeneration; Vision, Ocular;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE

Conference_Location

Boston, MA

ISSN

1557-170X

Print_ISBN

978-1-4244-4121-1

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2011.6091542

Filename

6091542